The CRALBP antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Mouse, Rat, and Drosophila/Arthropod antigen. The CRALBP antibody has been validated for the following applications: Immunoprecipitation, and Western Blot.
Description
Mouse monoclonal CRALBP antibody
CRALBP is a cytoplasmic protein, abundantly expressed in the retinal pigment epithelium (RPE) and Muller glia of the retina and in the pineal gland. Structurally, human CRALBP is a ~36- kDa monomeric protein, proposed to adopt an "open" or "closed" conformation, depending on whether it is carrying an endogenous ligand. CRALBP interacts structurally and functionally with 11-cis-retinol dehydrogenase (RDH5), an enzyme of the visual cycle in RPE. CRALBP is a member of the CRAL_TRIO family of proteins that share a lipid-binding domain derived from the yeast Sec14 protein